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ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis

Oxidative stress is a barrier of migration and metastasis for malignant melanoma cells. Consequently, reducing oxidative stress with the antioxidant N-acetylcysteine (NAC) stimulates melanoma cell migration in vitro and metastasis in vivo. However, it is not yet known whether the NAC effect is share...

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Detalles Bibliográficos
Autores principales: Kashif, Muhammad, Yao, Haidong, Schmidt, Sarah, Chen, Xue, Truong, Michelle, Tüksammel, Elin, Liu, Yiran, Bergo, Martin O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945759/
https://www.ncbi.nlm.nih.gov/pubmed/36774779
http://dx.doi.org/10.1016/j.redox.2023.102619