Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study

Based on its wide range of immunosuppressive properties, hydroxychloroquine (HCQ) is used for the treatment of several autoimmune diseases. Limited literature is available on the relationship between HCQ concentration and its immunosuppressive effect. To gain insight in this relationship, we perform...

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Detalles Bibliográficos
Autores principales: in ‘t Veld, Aliede E., Grievink, Hendrika W., van der Plas, Johan L., Eveleens Maarse, Boukje C., van Kraaij, Sebastiaan J. W., Woutman, Tess D., Schoonakker, Mascha, Klarenbeek, Naomi B., de Kam, Marieke L., Kamerling, Ingrid M. C., Jansen, Manon A. A., Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945836/
https://www.ncbi.nlm.nih.gov/pubmed/36811819
http://dx.doi.org/10.1007/s12026-023-09367-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945836/
https://www.ncbi.nlm.nih.gov/pubmed/36811819
http://dx.doi.org/10.1007/s12026-023-09367-3

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