PCIF1-mediated deposition of 5′-cap N(6),2′-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a major health problem worldwide. Due to the fast emergence of SARS-CoV-2 variants, understanding the molecular mechanisms of viral pathogenesis and developing novel inhibitors are essential and urgent. Here,...

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Detalles Bibliográficos
Autores principales: Wang, Lingling, Wang, Shaobo, Wu, Lujing, Li, Wanyu, Bray, William, Clark, Alex E., Gonzalez, Gwendolyn Michelle, Wang, Yinsheng, Carlin, Aaron F., Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945940/
https://www.ncbi.nlm.nih.gov/pubmed/36689652
http://dx.doi.org/10.1073/pnas.2210361120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945940/
https://www.ncbi.nlm.nih.gov/pubmed/36689652
http://dx.doi.org/10.1073/pnas.2210361120

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