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Cytosolic galectin-4 enchains bacteria, restricts their motility, and promotes inflammasome activation in intestinal epithelial cells

Galectin-4, a member of the galectin family of animal glycan-binding proteins (GBPs), is specifically expressed in gastrointestinal epithelial cells and is known to be able to bind microbes. However, its function in host-gut microbe interactions remains unknown. Here, we show that intracellular gale...

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Detalles Bibliográficos
Autores principales: Li, Chi-Shan, Lo, Tzu-Han, Tu, Ting-Jui, Chueh, Di-Yen, Yao, Cheng-I, Lin, Chun-Hung, Chen, Peilin, Liu, Fu-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945948/
https://www.ncbi.nlm.nih.gov/pubmed/36689650
http://dx.doi.org/10.1073/pnas.2207091120