The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme–iron from human hemoglobin

Streptococcus pyogenes (group A Streptococcus) is a clinically important microbial pathogen that requires iron in order to proliferate. During infections, S. pyogenes uses the surface displayed Shr receptor to capture human hemoglobin (Hb) and acquires its iron-laden heme molecules. Through a poorly...

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Detalles Bibliográficos
Autores principales: Macdonald, Ramsay, Mahoney, Brendan J., Soule, Jess, Goring, Andrew K., Ford, Jordan, Loo, Joseph A., Cascio, Duilio, Clubb, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945957/
https://www.ncbi.nlm.nih.gov/pubmed/36693107
http://dx.doi.org/10.1073/pnas.2211939120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945957/
https://www.ncbi.nlm.nih.gov/pubmed/36693107
http://dx.doi.org/10.1073/pnas.2211939120

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