Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force

Contraction in striated muscle is initiated by calcium binding to troponin complexes, but it is now understood that dynamic transition of myosin between resting, ordered OFF states on thick filaments and active, disordered ON states that can bind to thin filaments is critical in regulating muscle co...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Weikang, McMillen, Timothy S., Childers, Matthew Carter, Gong, Henry, Regnier, Michael, Irving, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945958/
https://www.ncbi.nlm.nih.gov/pubmed/36696446
http://dx.doi.org/10.1073/pnas.2207615120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945958/
https://www.ncbi.nlm.nih.gov/pubmed/36696446
http://dx.doi.org/10.1073/pnas.2207615120

Ejemplares similares