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Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury

Macrophage migration inhibitory factor (MIF) is a multifaced protein that plays important roles in multiple inflammatory conditions. However, the role of MIF in endothelial cell (EC) death under inflammatory condition remains largely unknown. Here we show that MIF actively promotes receptor-interact...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zou, Chengyu, Chen, Chen, Li, Sixuan, Zhu, Ziyu, Fan, Qiuyue, Pang, Rui, Li, Fengshi, Chen, Zengai, Wang, Zhenghong, Yu, Weifeng, Yuan, Junying, Li, Peiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945963/
https://www.ncbi.nlm.nih.gov/pubmed/36693098
http://dx.doi.org/10.1073/pnas.2219091120