Cargando…
Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury
Macrophage migration inhibitory factor (MIF) is a multifaced protein that plays important roles in multiple inflammatory conditions. However, the role of MIF in endothelial cell (EC) death under inflammatory condition remains largely unknown. Here we show that MIF actively promotes receptor-interact...
Autores principales: | Li, Yan, Zou, Chengyu, Chen, Chen, Li, Sixuan, Zhu, Ziyu, Fan, Qiuyue, Pang, Rui, Li, Fengshi, Chen, Zengai, Wang, Zhenghong, Yu, Weifeng, Yuan, Junying, Li, Peiying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945963/ https://www.ncbi.nlm.nih.gov/pubmed/36693098 http://dx.doi.org/10.1073/pnas.2219091120 |
Ejemplares similares
-
Effect of N-arachidonoyl-l-serine on human cerebromicrovascular endothelium()
por: Kino, Tomoyuki, et al.
Publicado: (2016) -
Stroke Exacerbates Cancer Progression by Upregulating LCN2 in PMN-MDSC
por: Huang, Tingting, et al.
Publicado: (2020) -
IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
por: Toth, Peter, et al.
Publicado: (2015) -
Transcriptome Profiling of Toxoplasma gondii-Infected Human Cerebromicrovascular Endothelial Cell Response to Treatment with Monensin
por: Harun, Mohammad S. R., et al.
Publicado: (2020) -
Targeting RIPK1 kinase for modulating inflammation in human diseases
por: Li, Wanjin, et al.
Publicado: (2023)