Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome

Gould syndrome is a rare multisystem disorder resulting from autosomal dominant mutations in the collagen-encoding genes COL4A1 and COL4A2. Human patients and Col4a1 mutant mice display brain pathology that typifies cerebral small vessel diseases (cSVDs), including white matter hyperintensities, dil...

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Detalles Bibliográficos
Autores principales: Yamasaki, Evan, Ali, Sher, Sanchez Solano, Alfredo, Thakore, Pratish, Smith, Megan, Wang, Xiaowei, Labelle-Dumais, Cassandre, Gould, Douglas B., Earley, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945977/
https://www.ncbi.nlm.nih.gov/pubmed/36693102
http://dx.doi.org/10.1073/pnas.2217327120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945977/
https://www.ncbi.nlm.nih.gov/pubmed/36693102
http://dx.doi.org/10.1073/pnas.2217327120

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