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Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching

Positive-strand RNA viruses replicate their genomes in virus-induced membrane vesicles, and the resulting RNA replication complexes are a major target for virus control. Nodavirus studies first revealed viral RNA replication proteins forming a 12-fold symmetric “crown” at the vesicle opening to the...

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Detalles Bibliográficos
Autores principales: Zhan, Hong, Unchwaniwala, Nuruddin, Rebolledo-Viveros, Andrea, Pennington, Janice, Horswill, Mark, Broadberry, Roma, Myers, Jonathan, den Boon, Johan A., Grant, Timothy, Ahlquist, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945985/
https://www.ncbi.nlm.nih.gov/pubmed/36693094
http://dx.doi.org/10.1073/pnas.2217412120