METTL3 is essential for normal progesterone signaling during embryo implantation via m(6)A-mediated translation control of progesterone receptor

Embryo implantation, a crucial step in human reproduction, is tightly controlled by estrogen and progesterone (P(4)) via estrogen receptor alpha and progesterone receptor (PGR), respectively. Here, we report that N(6)-methyladenosine (m(6)A), the most abundant mRNA modification in eukaryotes, plays...

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Detalles Bibliográficos
Autores principales: Zheng, Zhan-Hong, Zhang, Guo-Le, Jiang, Run-Fu, Hong, Yu-Qi, Zhang, Qing-Yan, He, Jia-Peng, Liu, Xin-Ru, Yang, Zhen-Shan, Yang, Liu, Jiang, Xing, Qu, Li-Jian, Ding, Chen-Hui, Xu, Yan-Wen, Yang, Shi-Hua, Liu, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945998/
https://www.ncbi.nlm.nih.gov/pubmed/36693099
http://dx.doi.org/10.1073/pnas.2214684120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945998/
https://www.ncbi.nlm.nih.gov/pubmed/36693099
http://dx.doi.org/10.1073/pnas.2214684120

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