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METTL3 is essential for normal progesterone signaling during embryo implantation via m(6)A-mediated translation control of progesterone receptor
Embryo implantation, a crucial step in human reproduction, is tightly controlled by estrogen and progesterone (P(4)) via estrogen receptor alpha and progesterone receptor (PGR), respectively. Here, we report that N(6)-methyladenosine (m(6)A), the most abundant mRNA modification in eukaryotes, plays...
Autores principales: | Zheng, Zhan-Hong, Zhang, Guo-Le, Jiang, Run-Fu, Hong, Yu-Qi, Zhang, Qing-Yan, He, Jia-Peng, Liu, Xin-Ru, Yang, Zhen-Shan, Yang, Liu, Jiang, Xing, Qu, Li-Jian, Ding, Chen-Hui, Xu, Yan-Wen, Yang, Shi-Hua, Liu, Ji-Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945998/ https://www.ncbi.nlm.nih.gov/pubmed/36693099 http://dx.doi.org/10.1073/pnas.2214684120 |
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