Efficacy and Safety of ARRY-371797 in LMNA-Related Dilated Cardiomyopathy: A Phase 2 Study

Lamin A/C gene (LMNA)-related dilated cardiomyopathy is a serious and life-threatening condition with a high unmet medical need. This phase 2 study assessed the effects of the oral selective p38 mitogen-activated protein kinase inhibitor ARRY-371797 on functional capacity and cardiac function in pat...

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Detalles Bibliográficos
Autores principales: MacRae, Calum A., Taylor, Matthew R.G., Mestroni, Luisa, Moses, John, Ashley, Euan A., Wheeler, Matthew T., Lakdawala, Neal K., Hershberger, Ray E., Sandor, Victor, Saunders, Michael E., Oliver, Colleen, Lee, Patrice A., Judge, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946172/
https://www.ncbi.nlm.nih.gov/pubmed/36515663
http://dx.doi.org/10.1161/CIRCGEN.122.003730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946172/
https://www.ncbi.nlm.nih.gov/pubmed/36515663
http://dx.doi.org/10.1161/CIRCGEN.122.003730

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