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NSUN2-mediated m(5)C methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections
5-Methylcytosine (m(5)C) is a widespread post-transcriptional RNA modification and is reported to be involved in manifold cellular responses and biological processes through regulating RNA metabolism. However, its regulatory role in antiviral innate immunity has not yet been elucidated. Here, we rep...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946332/ https://www.ncbi.nlm.nih.gov/pubmed/36748584 http://dx.doi.org/10.1080/22221751.2023.2178238 |