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NSUN2-mediated m(5)C methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections

5-Methylcytosine (m(5)C) is a widespread post-transcriptional RNA modification and is reported to be involved in manifold cellular responses and biological processes through regulating RNA metabolism. However, its regulatory role in antiviral innate immunity has not yet been elucidated. Here, we rep...

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Detalles Bibliográficos
Autores principales: Wang, Hongyun, Feng, Jiangpeng, Zeng, Cong, Liu, Jiejie, Fu, Zhiying, Wang, Dehe, Wang, Yafen, Zhang, Lu, Li, Jiali, Jiang, Ao, He, Miao, Cao, Yuanyuan, Yan, Kun, Tang, Hao, Guo, Deyin, Xu, Ke, Zhou, Xiang, Zhou, Li, Lan, Ke, Zhou, Yu, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946332/
https://www.ncbi.nlm.nih.gov/pubmed/36748584
http://dx.doi.org/10.1080/22221751.2023.2178238