Mitoxantrone targets both host and bacteria to overcome vancomycin resistance in Enterococcus faecalis

Antibiotic resistance critically limits treatment options for infection caused by opportunistic pathogens such as enterococci. Here, we investigate the antibiotic and immunological activity of the anticancer agent mitoxantrone (MTX) in vitro and in vivo against vancomycin-resistant Enterococcus faec...

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Detalles Bibliográficos
Autores principales: da Silva, Ronni A. G., Wong, Jun Jie, Antypas, Haris, Choo, Pei Yi, Goh, Karlyn, Jolly, Shreya, Liang, Cui, Tay Kwan Sing, Leona, Veleba, Mark, Hu, Guangan, Chen, Jianzhu, Kline, Kimberly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946351/
https://www.ncbi.nlm.nih.gov/pubmed/36812322
http://dx.doi.org/10.1126/sciadv.add9280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946351/
https://www.ncbi.nlm.nih.gov/pubmed/36812322
http://dx.doi.org/10.1126/sciadv.add9280

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