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miRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signaling

The ability to simultaneously modulate a set of genes for lineage-specific development has made miRNA an ideal master regulator for organogenesis. However, most miRNA deletions do not exhibit obvious phenotypic defects possibly due to functional redundancy. miRNAs are known to regulate skeletal line...

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Detalles Bibliográficos
Autores principales: Wang, Shumin, Maruyama, Eri O, Martinez, John, Lopes, Justin, Hsu, Trunee, Wu, Wencheng, Hsu, Wei, Maruyama, Takamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946445/
https://www.ncbi.nlm.nih.gov/pubmed/36752600
http://dx.doi.org/10.7554/eLife.79768