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Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most commonly diagnosed human prion disease caused by the abnormal misfolding of the ‘cellular’ prion protein (PrP(C)) into the transmissible ‘scrapie-type’ prion form (PrP(Sc)). Neuropathologic evaluation of brains with sCJD reveals abnormal PrP(Sc)...

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Detalles Bibliográficos
Autores principales: Goodwill, Vanessa S., Dryden, Ian, Choi, Jihee, De Lillo, Chiara, Soldau, Katrin, Llibre-Guerra, Jorge, Sanchez, Henry, Sigurdson, Christina J., Lin, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946801/
https://www.ncbi.nlm.nih.gov/pubmed/35803332
http://dx.doi.org/10.1016/j.exer.2022.109172