Inhibition of norepinephrine signaling during a sensitive period disrupts locus coeruleus circuitry and emotional behaviors in adulthood

Deficits in arousal and stress responsiveness are a feature of numerous psychiatric disorders including depression and anxiety. Arousal is supported by norepinephrine (NE) released from specialized brainstem nuclei, including the locus coeruleus (LC) neurons into cortical and limbic areas. During de...

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Detalles Bibliográficos
Autores principales: Meng, Qingyuan, Garcia-Garcia, Alvaro L., Dranovsky, Alex, Leonardo, E. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946949/
https://www.ncbi.nlm.nih.gov/pubmed/36813805
http://dx.doi.org/10.1038/s41598-023-29175-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946949/
https://www.ncbi.nlm.nih.gov/pubmed/36813805
http://dx.doi.org/10.1038/s41598-023-29175-x

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