Prolonged experimental CD4(+) T-cell depletion does not cause disease progression in SIV-infected African green monkeys

CD4(+) T-cell depletion is a hallmark of HIV infection, leading to impairment of cellular immunity and opportunistic infections, but its contribution to SIV/HIV-associated gut dysfunction is unknown. Chronically SIV-infected African Green Monkeys (AGMs) partially recover mucosal CD4(+) T-cells, main...

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Detalles Bibliográficos
Autores principales: Le Hingrat, Quentin, Sette, Paola, Xu, Cuiling, Rahmberg, Andrew R., Tarnus, Lilas, Annapureddy, Haritha, Kleinman, Adam, Brocca-Cofano, Egidio, Sivanandham, Ranjit, Sivanandham, Sindhuja, He, Tianyu, Capreri, Daniel J., Ma, Dongzhu, Estes, Jacob D., Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946951/
https://www.ncbi.nlm.nih.gov/pubmed/36813761
http://dx.doi.org/10.1038/s41467-023-36379-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946951/
https://www.ncbi.nlm.nih.gov/pubmed/36813761
http://dx.doi.org/10.1038/s41467-023-36379-2

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