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Nanoscale imaging of CD47 informs how plasma membrane modifications shape apoptotic cell recognition

CD47 recognized by its macrophage receptor SIRPα serves as a “don’t eat-me” signal protecting viable cells from phagocytosis. How this is abrogated by apoptosis-induced changes in the plasma membrane, concomitantly with exposure of phosphatidylserine and calreticulin “eat-me“ signals, is not well un...

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Detalles Bibliográficos
Autores principales: Dufour, Samy, Tacnet-Delorme, Pascale, Kleman, Jean-Philippe, Glushonkov, Oleksandr, Thielens, Nicole, Bourgeois, Dominique, Frachet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947010/
https://www.ncbi.nlm.nih.gov/pubmed/36813842
http://dx.doi.org/10.1038/s42003-023-04558-y