Gene knockdown in HaCaT cells by small interfering RNAs entrapped in grapefruit-derived extracellular vesicles using a microfluidic device

Small interfering RNAs (siRNAs) knockdown the expression of target genes by causing mRNA degradation and are a promising therapeutic modality. In clinical practice, lipid nanoparticles (LNPs) are used to deliver RNAs, such as siRNA and mRNA, into cells. However, these artificial nanoparticles are to...

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Detalles Bibliográficos
Autores principales: Itakura, Shoko, Shohji, Ayaka, Amagai, Sayaka, Kitamura, Masashi, Takayama, Kozo, Sugibayashi, Kenji, Todo, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947018/
https://www.ncbi.nlm.nih.gov/pubmed/36813850
http://dx.doi.org/10.1038/s41598-023-30180-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947018/
https://www.ncbi.nlm.nih.gov/pubmed/36813850
http://dx.doi.org/10.1038/s41598-023-30180-3

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