CoQ(10) reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation

PURPOSE: Most monotherapies available against glioblastoma multiforme (GBM) target individual hallmarks of this aggressive brain tumor with minimal success. In this article, we propose a therapeutic strategy using coenzyme Q(10) (CoQ(10)) as a pleiotropic factor that crosses the blood–brain barrier...

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Detalles Bibliográficos
Autores principales: Frontiñán-Rubio, Javier, Llanos-González, Emilio, García-Carpintero, Sonia, Peinado, Juan Ramón, Ballesteros-Yáñez, Inmaculada, Rayo, Margarita Villar, de la Fuente, José, Pérez-García, Víctor M., Perez-Romasanta, Luis A., Malumbres, Marcos, Alcaín, Francisco J., Durán-Prado, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947058/
https://www.ncbi.nlm.nih.gov/pubmed/36319818
http://dx.doi.org/10.1007/s13402-022-00734-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947058/
https://www.ncbi.nlm.nih.gov/pubmed/36319818
http://dx.doi.org/10.1007/s13402-022-00734-0

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