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Soluble Klotho protects against glomerular injury through regulation of ER stress response

αKlotho (Klotho) has well established renoprotective effects; however, the molecular pathways mediating its glomerular protection remain incompletely understood. Recent studies have reported that Klotho is expressed in podocytes and protects glomeruli through auto- and paracrine effects. Here, we ex...

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Detalles Bibliográficos
Autores principales: Charrin, Emmanuelle, Dabaghie, Dina, Sen, Ilke, Unnersjö-Jess, David, Möller-Hackbarth, Katja, Burmakin, Mikhail, Mencke, Rik, Zambrano, Sonia, Patrakka, Jaakko, Olauson, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947099/
https://www.ncbi.nlm.nih.gov/pubmed/36813870
http://dx.doi.org/10.1038/s42003-023-04563-1