Cargando…
Soluble Klotho protects against glomerular injury through regulation of ER stress response
αKlotho (Klotho) has well established renoprotective effects; however, the molecular pathways mediating its glomerular protection remain incompletely understood. Recent studies have reported that Klotho is expressed in podocytes and protects glomeruli through auto- and paracrine effects. Here, we ex...
Autores principales: | Charrin, Emmanuelle, Dabaghie, Dina, Sen, Ilke, Unnersjö-Jess, David, Möller-Hackbarth, Katja, Burmakin, Mikhail, Mencke, Rik, Zambrano, Sonia, Patrakka, Jaakko, Olauson, Hannes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947099/ https://www.ncbi.nlm.nih.gov/pubmed/36813870 http://dx.doi.org/10.1038/s42003-023-04563-1 |
Ejemplares similares
-
Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes
por: He, Bing, et al.
Publicado: (2021) -
Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement
por: Schwarz, Angelina, et al.
Publicado: (2019) -
Inactivation of mediator complex protein 22 in podocytes results in intracellular vacuole formation, podocyte loss and premature death
por: Rodriguez, Patricia Q., et al.
Publicado: (2020) -
FYVE domain-containing protein ZFYVE28 regulates EGFR-signaling in podocytes but is not critical for the function of filtration barrier in mice
por: Zambrano, Sonia, et al.
Publicado: (2018) -
Renal Klotho is Reduced in Septic Patients and Pretreatment With Recombinant Klotho Attenuates Organ Injury in Lipopolysaccharide-Challenged Mice
por: Jou-Valencia, Daniela, et al.
Publicado: (2018)