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Regulating macrophage-MSC interaction to optimize BMP-2-induced osteogenesis in the local microenvironment
Bone morphogenetic protein (BMP-2) has been approved by the FDA to promote bone regeneration, but uncertain osteogenic effect and dose-dependent side effects may occur. Osteoimmunomodulation plays an important role in growth factor-based osteogenesis. Here, we explored how proinflammatory signals af...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947106/ https://www.ncbi.nlm.nih.gov/pubmed/36844362 http://dx.doi.org/10.1016/j.bioactmat.2023.02.001 |