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Regulating macrophage-MSC interaction to optimize BMP-2-induced osteogenesis in the local microenvironment

Bone morphogenetic protein (BMP-2) has been approved by the FDA to promote bone regeneration, but uncertain osteogenic effect and dose-dependent side effects may occur. Osteoimmunomodulation plays an important role in growth factor-based osteogenesis. Here, we explored how proinflammatory signals af...

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Detalles Bibliográficos
Autores principales: Jiang, Fei, Qi, Xuanyu, Wu, Xiaolin, Lin, Sihan, Shi, Junfeng, Zhang, Wenjie, Jiang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947106/
https://www.ncbi.nlm.nih.gov/pubmed/36844362
http://dx.doi.org/10.1016/j.bioactmat.2023.02.001