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Catalyst free one pot three components synthesis of 2-iminothiazoles from nitroepoxides and thiourea

Nitroepoxides were introduced as efficient substrates for the one-pot three-component synthesis of 2-iminothiazoles under catalyst-free conditions. Reaction of amines, isothiocyanates, and nitroepoxides in THF at 10–15 °C afforded corresponding 2-iminothiazoles in high to excellent yields. The react...

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Detalles Bibliográficos
Autores principales: Badali, Elham, Ziyaei Halimehjani, Azim, Habibi, Azizollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947138/
https://www.ncbi.nlm.nih.gov/pubmed/36813887
http://dx.doi.org/10.1038/s41598-023-30243-5