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Dynamic state of plasmid genomic architectures resulting from XerC/D-mediated site-specific recombination in Acinetobacter baumannii Rep_3 superfamily resistance plasmids carrying bla(OXA-58)- and TnaphA6-resistance modules

The acquisition of bla(OXA) genes encoding different carbapenem-hydrolyzing class-D β-lactamases (CHDL) represents a main determinant of carbapenem resistance in the nosocomial pathogen Acinetobacter baumannii. The bla(OXA-58) gene, in particular, is generally embedded in similar resistance modules...

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Detalles Bibliográficos
Autores principales: Giacone, Lucía, Cameranesi, M. Marcela, Sanchez, Rocío I., Limansky, Adriana S., Morán-Barrio, Jorgelina, Viale, Alejandro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947245/
https://www.ncbi.nlm.nih.gov/pubmed/36846794
http://dx.doi.org/10.3389/fmicb.2023.1057608