Synthesis, molecular docking study and anticancer activity of novel 1,3,4-oxadiazole derivatives as potential tubulin inhibitors

The current study reports on the synthesis and anticancer efficacy of novel oxadiazole derivatives (8a-f) as tubulin polymerization inhibitors. NMR, mass, and elemental studies were used to confirm the newly produced compounds. In contrast to the conventional medicine colchicine, compounds 8e and 8f...

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Detalles Bibliográficos
Autores principales: Yousef, Tarek A., Alhamzani, Abdulrahman G., Abou-Krisha, Mortaga M., Kanthimathi, G., Raghu, M.S., Kumar, K. Yogesh, Prashanth, M.K., Jeon, Byong-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947267/
https://www.ncbi.nlm.nih.gov/pubmed/36846693
http://dx.doi.org/10.1016/j.heliyon.2023.e13460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947267/
https://www.ncbi.nlm.nih.gov/pubmed/36846693
http://dx.doi.org/10.1016/j.heliyon.2023.e13460

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