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Systematic diet composition swap in a mouse genome-scale metabolic model reveals determinants of obesogenic diet metabolism in liver cancer

Dietary nutrient availability and gene expression, together, influence tissue metabolic activity. Here, we explore whether altering dietary nutrient composition in the context of mouse liver cancer suffices to overcome chronic gene expression changes that arise from tumorigenesis and western-style d...

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Detalles Bibliográficos
Autores principales: Clasen, Frederick, Nunes, Patrícia M., Bidkhori, Gholamreza, Bah, Nourdine, Boeing, Stefan, Shoaie, Saeed, Anastasiou, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947310/
https://www.ncbi.nlm.nih.gov/pubmed/36844450
http://dx.doi.org/10.1016/j.isci.2023.106040