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Systematic diet composition swap in a mouse genome-scale metabolic model reveals determinants of obesogenic diet metabolism in liver cancer
Dietary nutrient availability and gene expression, together, influence tissue metabolic activity. Here, we explore whether altering dietary nutrient composition in the context of mouse liver cancer suffices to overcome chronic gene expression changes that arise from tumorigenesis and western-style d...
Autores principales: | Clasen, Frederick, Nunes, Patrícia M., Bidkhori, Gholamreza, Bah, Nourdine, Boeing, Stefan, Shoaie, Saeed, Anastasiou, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947310/ https://www.ncbi.nlm.nih.gov/pubmed/36844450 http://dx.doi.org/10.1016/j.isci.2023.106040 |
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