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Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model

Aberrant neurodevelopment is a core deficit of autism spectrum disorder (ASD). Here we ask whether a non-genetic factor, prenatal exposure to the environmental pollutant methylmercury (MeHg), is a contributing factor in ASD onset. We showed that adult mice prenatally exposed to non-apoptotic MeHg ex...

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Detalles Bibliográficos
Autores principales: Loan, Allison, Leung, Joseph Wai-Hin, Cook, David P., Ko, Chelsea, Vanderhyden, Barbara C., Wang, Jing, Chan, Hing Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947313/
https://www.ncbi.nlm.nih.gov/pubmed/36843845
http://dx.doi.org/10.1016/j.isci.2023.106093