Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation

The highly conserved endoplasmic reticulum (ER) protein translocation channel contains one nonessential subunit, Sec61β/Sbh1, whose function is poorly understood so far. Its intrinsically unstructured cytosolic domain makes transient contact with ER-targeting sequences in the cytosolic channel vesti...

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Detalles Bibliográficos
Autores principales: Barbieri, Guido, Simon, Julien, Lupusella, Cristina R., Pereira, Fabio, Elia, Francesco, Meyer, Hadar, Schuldiner, Maya, Hanes, Steven D., Nguyen, Duy, Helms, Volkhard, Römisch, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947333/
https://www.ncbi.nlm.nih.gov/pubmed/36639027
http://dx.doi.org/10.1016/j.jbc.2023.102895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947333/
https://www.ncbi.nlm.nih.gov/pubmed/36639027
http://dx.doi.org/10.1016/j.jbc.2023.102895

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