CRISPR activation screening in a mouse model for drivers of hepatocellular carcinoma growth and metastasis

Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality worldwide. Here we described a genome-wide screen by CRISPR activation (CRISPRa) library in vivo for drivers of HCC growth and metastasis. Pathological results showed the cell population formed highly metastatic tumors...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Bei, Ren, Zhiyao, Zheng, Hongmei, Lin, Meilan, Chen, Guobing, Luo, Oscar Junhong, Zhu, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947337/
https://www.ncbi.nlm.nih.gov/pubmed/36843840
http://dx.doi.org/10.1016/j.isci.2023.106099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947337/
https://www.ncbi.nlm.nih.gov/pubmed/36843840
http://dx.doi.org/10.1016/j.isci.2023.106099

Ejemplares similares