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A novel strategy for precise prognosis management and treatment option in colon adenocarcinoma with TP53 mutations

BACKGROUND: TP53 is one of the most frequent mutated genes in colon cancer. Although colon cancer with TP53 mutations has a high risk of metastasis and worse prognosis generally, it showed high heterogeneity clinically. METHODS: A total of 1,412 colon adenocarcinoma (COAD) samples were obtained from...

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Detalles Bibliográficos
Autores principales: Niu, Lei, Liu, Langbiao, Cai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947352/
https://www.ncbi.nlm.nih.gov/pubmed/36843983
http://dx.doi.org/10.3389/fsurg.2023.1079129