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MARS2 drives metabolic switch of non-small-cell lung cancer cells via interaction with MCU
Mitochondrial methionyl-tRNA synthetase (MARS2) canonically mediates the formation of fMet-tRNA(i)(fMet) for mitochondrial translation initiation. Mitochondrial calcium uniporter (MCU) is a major gate of Ca(2+) flux from cytosol into the mitochondrial matrix. We found that MARS2 interacts with MCU a...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947422/ https://www.ncbi.nlm.nih.gov/pubmed/36774778 http://dx.doi.org/10.1016/j.redox.2023.102628 |