MARS2 drives metabolic switch of non-small-cell lung cancer cells via interaction with MCU

Mitochondrial methionyl-tRNA synthetase (MARS2) canonically mediates the formation of fMet-tRNA(i)(fMet) for mitochondrial translation initiation. Mitochondrial calcium uniporter (MCU) is a major gate of Ca(2+) flux from cytosol into the mitochondrial matrix. We found that MARS2 interacts with MCU a...

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Detalles Bibliográficos
Autores principales: Son, Juhyeon, Jung, Okkeun, Kim, Jong Heon, Park, Kyu Sang, Kweon, Hee-Seok, Nguyen, Nhung Thi, Lee, Yu Jin, Cha, Hansol, Lee, Yejin, Tran, Quangdon, Seo, Yoona, Park, Jongsun, Choi, Jungwon, Cheong, Heesun, Lee, Sang Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947422/
https://www.ncbi.nlm.nih.gov/pubmed/36774778
http://dx.doi.org/10.1016/j.redox.2023.102628

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