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PriPath: identifying dysregulated pathways from differential gene expression via grouping, scoring, and modeling with an embedded feature selection approach

BACKGROUND: Cell homeostasis relies on the concerted actions of genes, and dysregulated genes can lead to diseases. In living organisms, genes or their products do not act alone but within networks. Subsets of these networks can be viewed as modules that provide specific functionality to an organism...

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Detalles Bibliográficos
Autores principales: Yousef, Malik, Ozdemir, Fatma, Jaber, Amhar, Allmer, Jens, Bakir-Gungor, Burcu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947447/
https://www.ncbi.nlm.nih.gov/pubmed/36823571
http://dx.doi.org/10.1186/s12859-023-05187-2