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CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells
Development of the hybridoma technology by Köhler and Milstein (1975) has revolutionized the immunological field by enabling routine use of monoclonal antibodies (mAbs) in research and development efforts, resulting in their successful application in the clinic today. While recombinant good manufact...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bio-Protocol
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947551/ https://www.ncbi.nlm.nih.gov/pubmed/36845533 http://dx.doi.org/10.21769/BioProtoc.4613 |