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CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells

Development of the hybridoma technology by Köhler and Milstein (1975) has revolutionized the immunological field by enabling routine use of monoclonal antibodies (mAbs) in research and development efforts, resulting in their successful application in the clinic today. While recombinant good manufact...

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Detalles Bibliográficos
Autores principales: Gall, Camille Le M., Fennemann, Felix L., Van Der Schoot, Johan M. S., Scheeren, Ferenc A., Verdoes, Martijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947551/
https://www.ncbi.nlm.nih.gov/pubmed/36845533
http://dx.doi.org/10.21769/BioProtoc.4613