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Cyclooxygenase‑2 contributes to the hypoxia‑induced aggravation of the neuroinflammation response stimulated by lipopolysaccharide in microglia

Hypoxia and neuroinflammation are key risk factors involved in various pathophysiological neural disorders. Hypoxia can aggravate neuroinflammation in vitro and in vivo; however, the underlying mechanisms remain unknown. In the present study, hypoxia [either 3 or 1% oxygen (O(2))] increased lipopoly...

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Detalles Bibliográficos
Autores principales: Yang, Yifan, Geng, Yanan, Cheng, Xiang, Gao, Jiayue, Shi, Zibi, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947573/
https://www.ncbi.nlm.nih.gov/pubmed/36845947
http://dx.doi.org/10.3892/etm.2023.11822