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Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway

Neonatal hypoxic-ischemic encephalopathy (HIE) is considered a major cause of death and long-term neurological injury in newborns. Studies have demonstrated that oxidative stress and apoptosis play a major role in the progression of neonatal HIE. Echinocystic acid (EA), a natural plant extract, show...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Chen, Ling, Zheng, Da, Liu, Jian-Xia, Liu, Chao, Qi, Shao-Hua, Hu, Peng-Chao, Yang, Xiao-Fei, Min, Jia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947717/
https://www.ncbi.nlm.nih.gov/pubmed/36843928
http://dx.doi.org/10.3389/fphar.2023.1103265