Cargando…
Modeling C3 glomerulopathies: C3 convertase regulation on an extracellular matrix surface
INTRODUCTION: C3 glomerulopathies (C3G) are ultra-rare complement-mediated diseases that lead to end-stage renal disease (ESRD) within 10 years of diagnosis in ~50% of patients. Overactivation of the alternative pathway (AP) of complement in the fluid phase and on the surface of the glomerular endot...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947773/ https://www.ncbi.nlm.nih.gov/pubmed/36846022 http://dx.doi.org/10.3389/fimmu.2022.1073802 |