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Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammation

INTRODUCTION: There is an unmet medical need for effective anti-inflammatory agents for the treatment of acute and post-acute lung inflammation caused by respiratory viruses. The semi-synthetic polysaccharide, Pentosan polysulfate sodium (PPS), an inhibitor of NF-kB activation, was investigated for...

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Detalles Bibliográficos
Autores principales: Krishnan, Ravi, Stapledon, Catherine J. M., Mostafavi, Helen, Freitas, Joseph R., Liu, Xiang, Mahalingam, Suresh, Zaid, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947849/
https://www.ncbi.nlm.nih.gov/pubmed/36845136
http://dx.doi.org/10.3389/fimmu.2023.1030879