Gasdermin D pore-forming activity is redox-sensitive

Reactive oxygen species (ROS) regulate the activities of inflammasomes, which are innate immune signaling organelles that induce pyroptosis. The mechanisms by which ROS control inflammasome activities are unclear and may be multifaceted. Herein, we report that the protein gasdermin D (GSDMD), which...

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Detalles Bibliográficos
Autores principales: Devant, Pascal, Boršić, Elvira, Ngwa, Elsy M., Xiao, Haopeng, Chouchani, Edward T., Thiagarajah, Jay R., Hafner-Bratkovič, Iva, Evavold, Charles L., Kagan, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947919/
https://www.ncbi.nlm.nih.gov/pubmed/36662620
http://dx.doi.org/10.1016/j.celrep.2023.112008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9947919/
https://www.ncbi.nlm.nih.gov/pubmed/36662620
http://dx.doi.org/10.1016/j.celrep.2023.112008

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