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Synthesis, Molecular Docking, and Biological Evaluation of a New Series of Benzothiazinones and Their Benzothiazinyl Acetate Derivatives as Anticancer Agents against MCF-7 Human Breast Cancer Cells and as Anti-Inflammatory Agents

[Image: see text] Six 1,4-benzothiazin-3-ones (2a–f) and four benzothiazinyl acetate derivatives (3a–d) were synthesized and characterized by various spectroscopic methods, namely, (1)H NMR, (13)C NMR, IR, MS, and elemental analysis. The cytotoxic effects of the compounds were assessed against MCF-7...

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Detalles Bibliográficos
Autores principales: Ramzan, Farhat, Nabi, Syed Ayaz, Lone, Mehak Saba, Imtiyaz, Khalid, Urooj, Laraib, Vishakha, Vishakha, Sharma, Kalicharan, Rizvi, M. Moshahid A., Shafi, Syed, Samim, Mohammed, Bano, Sameena, Javed, Kalim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948161/
https://www.ncbi.nlm.nih.gov/pubmed/36844525
http://dx.doi.org/10.1021/acsomega.2c07153