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Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity

[Image: see text] The structure-based design introduced indoles as an essential motif in designing new selective estrogen receptor modulators employed for treating breast cancer. Therefore, here, a series of synthesized vanillin-substituted indolin-2-ones were screened against the NCI-60 cancer cell...

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Detalles Bibliográficos
Autores principales: Bender, Onur, Celik, Ismail, Dogan, Rumeysa, Atalay, Arzu, Shoman, Mai E., Ali, Taha F. S., Beshr, Eman A. M., Mohamed, Mahmoud, Alaaeldin, Eman, Shawky, Ahmed M., Awad, Eman M., Ahmed, Al-Shaimaa F., Younes, Kareem M., Ansari, Mukhtar, Anwar, Sirajudheen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948168/
https://www.ncbi.nlm.nih.gov/pubmed/36844536
http://dx.doi.org/10.1021/acsomega.2c07793