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Bio-Oriented Synthesis of Novel Polyhydroquinoline Derivatives as α-Glucosidase Inhibitor for Management of Diabetes

[Image: see text] Polyhydroquinoline derivatives (1-15) were synthesized through an unsymmetrical Hantzsch reaction in excellent yields by treating 3,5-dibromo-4-hydroxybenzaldehyde, dimedone, ammonium acetate, and ethyl acetoacetate in ethanol solvent. The structures of the synthesized compounds (1...

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Detalles Bibliográficos
Autores principales: Talab, Faiz, Ullah, Saeed, Alam, Aftab, Halim, Sobia Ahsan, Rehman, Najeeb Ur, Zainab, Ali, Mumtaz, Latif, Abdul, Khan, Ajmal, Al-Harrasi, Ahmed, Ahmad, Manzoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948207/
https://www.ncbi.nlm.nih.gov/pubmed/36844517
http://dx.doi.org/10.1021/acsomega.2c05390