Design and Development of Novel Glitazones for Activation of PGC-1α Signaling Via PPAR-γ Agonism: A Promising Therapeutic Approach against Parkinson’s Disease

[Image: see text] Herein, we rationally designed and developed two novel glitazones (G1 and G2) to target peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α) signaling through peroxisome proliferator-activated receptors (PPAR)-γ agonism as a therapeutic for Parkinson’s dise...

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Detalles Bibliográficos
Autores principales: Prabhakaran, Prabitha, Nadig, Abhishek, M, Sahyadri, Tuladhar, Sunanda, Raju, Ruby Mariam, Chidambaram, Saravana Babu, Kempaiah, Bettadaiah Bheemanakere, Raghavendra, Nulgumnalli Manjunathaiah, Kumar BR, Prashantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948211/
https://www.ncbi.nlm.nih.gov/pubmed/36844520
http://dx.doi.org/10.1021/acsomega.2c07521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948211/
https://www.ncbi.nlm.nih.gov/pubmed/36844520
http://dx.doi.org/10.1021/acsomega.2c07521

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