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Mutations in immunodeficiency-related genes may increase the risk of infection after CAR-T-cell therapy: a report of two cases

BACKGROUND: Chimeric antigen receptor T-cell therapy (CAR-T) has yielded unprecedented efficacy in B-cell malignancies. With the increasing use of CAR-T-cell therapy, infection has become one of the major concerns after CAR-T-cell infusion. Some patients even develop refractory or recurrent infectio...

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Detalles Bibliográficos
Autores principales: Wang, Di, He, Li, Li, Chunhui, Xu, Menglei, Yu, Qiuxia, Almeida, Varlene Daniela Fernandes, Que, Yimei, Xu, Yanjie, Xiao, Yi, Li, Chunrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948332/
https://www.ncbi.nlm.nih.gov/pubmed/36814216
http://dx.doi.org/10.1186/s12879-023-08070-w