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Mutations in immunodeficiency-related genes may increase the risk of infection after CAR-T-cell therapy: a report of two cases
BACKGROUND: Chimeric antigen receptor T-cell therapy (CAR-T) has yielded unprecedented efficacy in B-cell malignancies. With the increasing use of CAR-T-cell therapy, infection has become one of the major concerns after CAR-T-cell infusion. Some patients even develop refractory or recurrent infectio...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948332/ https://www.ncbi.nlm.nih.gov/pubmed/36814216 http://dx.doi.org/10.1186/s12879-023-08070-w |