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Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system

OBJECTIVES: To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease nephropathy (FDN). METHODS: First, we generated hiPSC line using peripheral blood mononuclear cells (PBMCs) from two male FD-patients...

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Detalles Bibliográficos
Autores principales: Cui, Sheng, Fang, Xianying, Lee, Hanbi, Shin, Yoo Jin, Koh, Eun-Sil, Chung, Sungjin, Park, Hoon Suk, Lim, Sun Woo, Lee, Kang In, Lee, Jae Young, Yang, Chul Woo, Chung, Byung Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948377/
https://www.ncbi.nlm.nih.gov/pubmed/36814269
http://dx.doi.org/10.1186/s12967-023-03992-0