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Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system
OBJECTIVES: To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease nephropathy (FDN). METHODS: First, we generated hiPSC line using peripheral blood mononuclear cells (PBMCs) from two male FD-patients...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948377/ https://www.ncbi.nlm.nih.gov/pubmed/36814269 http://dx.doi.org/10.1186/s12967-023-03992-0 |